| Drug Name: | Dosage: | Best Price: | Where To Buy Online? |
|---|---|---|---|
| Restasis (Cyclosporine) 0.05% | 30 x 0.4ml | $199.95 | Order Now |
| Cyclosporine Ophthalmic (Generic) 0.05% | 1 x 3ml | $64.95 | Order Now |
Restasis (Cyclosporine Ophthalmic Emulsion 0.05%) is a prescription medication used to treat chronic dry eye syndrome (DES). Unlike artificial tears, which provide temporary relief, Restasis reduces inflammation and restores natural tear production. This makes it the only medication of its kind that works at the cellular level, suppressing immune cell activity that damages the tear glands.
It is particularly effective for cases of chronic dry eye that do not respond to standard lubricating drops. It is also beneficial for patients with autoimmune disorders, post-laser eye surgery dryness, meibomian gland dysfunction, and chronic eyelid inflammation.
Mechanism of Action
Restasis contains cyclosporine, a calcineurin inhibitor that suppresses T-lymphocyte activity, preventing them from attacking the lacrimal glands.
The primary cause of dry eye syndrome is chronic inflammation, which leads to:
- Reduced tear production
- Damage to the tear film
- Eye irritation, redness, and a gritty sensation
- Light sensitivity and eye fatigue
Unlike artificial tears, which only provide short-term relief, Restasis works to restore lacrimal gland function and combat the underlying inflammation.
Indications for Use
Restasis is prescribed when dry eye syndrome has an inflammatory origin and causes damage to the tear-producing cells.
- Chronic dry eye syndrome that does not improve with artificial tears
- Sjögren’s syndrome, where the immune system attacks the lacrimal and salivary glands
- Post-surgical dry eye (e.g., after LASIK, PRK, or cataract surgery)
- Contact lens-induced eye irritation
- Chronic blepharitis and meibomian gland dysfunction
- Autoimmune diseases affecting tear production
Restasis is intended for long-term use because its effects are cumulative and develop gradually.
How to Use
The medication is supplied in single-use vials (0.4 ml each). Since Restasis does not contain preservatives, it should not be stored after opening.
Standard Dosage:
- One drop in each eye, twice daily
- 12-hour interval between doses
- Shake the vial before use
- Wait at least 15 minutes before using artificial tears
Some patients may experience mild burning, stinging, or irritation after application, which usually resolves within minutes.
When to Expect Results
Restasis does not provide immediate relief as it works by gradually reducing inflammation.
- 1 month: Slight reduction in irritation, but tear production remains low
- 2–3 months: Improved tear film stability, reduced dryness
- 6 months: Full restoration of lacrimal gland function
The minimum course duration is 6 months, as this is the time needed for full recovery of the tear glands.
Can Restasis Be Used with Other Medications?
Restasis can be combined with other ophthalmic treatments, but proper intervals between drops should be maintained.
Safe Combinations:
- Artificial tears (wait 15 minutes before applying Restasis)
- Glaucoma medications (use at different times of the day)
- Antibiotic eye drops (if prescribed by an eye specialist)
Avoid Using With:
- Steroid eye drops (e.g., Dexamethasone, Pred Forte) as they may mask inflammation
- Unprescribed antibiotics
- Contact lenses immediately after application (wait 15 minutes)
What to Do If You Miss a Dose?
Restasis must be used consistently since its effects build up over time.
- If a dose is missed, apply it as soon as possible.
- If more than 6 hours have passed, do not double the dose; continue with the regular schedule.
- Doubling the dose will not speed up the effects and may cause irritation.
Who Should Avoid Restasis?
The medication should not be used in the following cases:
- Active bacterial or viral eye infections
- Allergy to cyclosporine
- Children under 16 (safety has not been studied in this age group)
- Acute eye inflammation
During pregnancy and breastfeeding, Restasis should only be used if necessary, as its effects on the fetus remain unclear.
Possible Side Effects
Restasis is prescribed to increase tear production in patients with chronic dry eye disease caused by inflammation. While the medication is generally well tolerated, some side effects may occur.
Common Side Effects
- Burning or stinging sensation in the eyes after application
- Redness of the eye
- Blurred vision
- Watery eyes
- Eye discomfort or irritation
Less Common but Possible Side Effects
- Eyelid inflammation (blepharitis)
- Foreign body sensation in the eye
- Allergic reactions (itching, swelling, rash around the eye area)
- Increased sensitivity to light (photophobia)
Serious Side Effects (Rare)
- Severe eye pain or excessive redness
- Swelling of the eye or eyelid
- Signs of an eye infection (discharge, crusting, severe swelling)
- Severe allergic reactions (hives, difficulty breathing, swelling of the face, lips, or tongue)
If any serious side effects occur, medical attention may be necessary. Regular follow-ups are recommended to monitor long-term use and ensure the medication's effectiveness and safety.
Advantages of Restasis
- Treats the root cause of dry eye, not just symptoms
- Non-addictive—restores natural tear production
- Safe for long-term use, unlike steroid drops
- Proven effective for autoimmune-related dry eye
- Suitable for post-surgical dryness, chronic blepharitis, and meibomian gland dysfunction
FAQ
Restasis can be used long-term for chronic dry eye disease as it helps increase tear production over time. Many patients continue using it for months or even years to maintain effectiveness. Regular evaluations are recommended to monitor progress and determine ongoing necessity.
Restasis is classified as a Category C medication, meaning its effects on pregnancy have not been fully studied. It should only be used if the potential benefits outweigh the risks. Consulting a healthcare provider is essential before using Restasis during pregnancy.
Restasis is typically used continuously, with noticeable improvements often taking several months. Patients are usually advised to continue treatment as long as symptoms persist and benefits are observed. Discontinuation should be based on professional evaluation.
If Restasis does not provide relief after several months, alternative treatments such as punctal plugs, serum tears, or other prescription eye drops may be considered. Consulting an eye specialist can help identify the most suitable approach for managing chronic dry eye.
Restasis is a unique medication that helps patients suffering from chronic dry eye syndrome. It addresses the root cause of the condition, rather than just providing temporary relief, making it ideal for long-term use.
If you experience persistent dryness, irritation, grittiness, light sensitivity, and eye discomfort, Restasis can help restore natural tear production and improve eye comfort.